Knight Cancer Research Building

A workplace for true team science

Evening exterior view of a multi-story research building with floor-to-ceiling windows wrapping around each level, revealing illuminated interior workspaces. The structure features a series of white horizontal panels and vertical fins, with landscaped areas and street lighting surrounding the base. Elevated roadways and city buildings are visible in the background.

Client
Oregon Health & Science University
Location
Oregon, United States
Size
320,000 square feet
Status
Completed
LEED Platinum

Oregon Health and Science University’s Knight Cancer Institute envisioned a state-of-the-art research facility to support a team science approach, and the Knight Cancer Research Building fulfills this vision. It has been instrumental in recruiting approximately 250 of the world’s leading cancer researchers and physicians dedicated to curing cancer.

Located on Portland’s South Waterfront, our team designed the building to encourage radical levels of interaction and collaboration among researchers from different scientific disciplines — all to transform how cancer research is done. It includes open work spaces, large lab areas congregated at the center of four research floors and common areas on several floors where scientists share advanced lab equipment.

Oregon Health & Science University Knight Cancer Research Building
Oregon Health & Science University Knight Cancer Research Building
Oregon Health & Science University Knight Cancer Research Building

Breaking down silos to promote collaboration

Reducing the number of research floors and increasing the size of each floor allowed us to incorporate communicating stairs, which form functional and visual connections between floors and between research teams. The experimentalist laboratory and office suites are organized in interconnected “neighborhoods.”

These neighborhoods retain the modest scale researchers prefer, while providing the flexibility to reallocate space as needed. The extensive use of glass walls creates visual connections that reinforce the collective identity of the Knight Cancer Institute and allow more daylight into the building.

Oregon Health & Science University Knight Cancer Research Building
Oregon Health & Science University Knight Cancer Research Building
Oregon Health & Science University Knight Cancer Research Building
Oregon Health & Science University Knight Cancer Research Building

Human-centered spaces

The workspaces are visually connected through extensive glass partitions, fostering transparency and collaboration. Quiet areas offer researchers a retreat for reflective, private work. A central kitchen encourages social interaction during meals, while an intellectual lounge with an adjoining roof terrace provides a relaxing space for researchers to unwind and share discoveries. Casual seating throughout the building promotes chance encounters, nurturing a culture of collective goals.

The ground-floor conference center features a 200-seat auditorium and multiple meeting rooms, accommodating a variety of events. A retail café and additional amenities create a public zone that contributes to the long-term development of the research campus.

Interior view of a communal workspace with floor-to-ceiling windows along one side, offering natural light and views outside. The space includes long tables with chairs, high-top tables with stools, and a meeting area partially enclosed by sliding panels. A dark perforated ceiling is embedded with small lights, and wood accents frame parts of the ceiling and wall openings.
Oregon Health & Science University Knight Cancer Research Building
Oregon Health & Science University Knight Cancer Research Building

Testimonials

  • I’m thrilled to see team science realized in this building. As a researcher myself, I appreciate the vision to create a space that encourages the sharing of information and ideas. This science building is unlike any other at OHSU.

    Tiffani Howard, Ph.D Project Liaison

Healthy materials

As a facility focused on treating cancer, the LEED Platinum building was designed to meet the highest health and wellness standards. The materials selected are toxin-free and carcinogen-free. The team utilized a first of its kind matrix that maps product choices by sourcing, manufacturing, certification, and chemical content, with a special focus on identifying the source of carcinogens in the built environment. Referencing standards from the Living Building Challenge, IARC, and GreenScreen Benchmark, the unique evaluation tool served to educate the owner and design team on the impact that our decisions have on occupant health, as well as further the mission of the Institute to end cancer as we know it.

Oregon Health & Science University Knight Cancer Research Building